Haemorrhagic diathesis ( coagulopathy, platelet disorder)
1. Big picture
Haemorrhagic diathesis means an abnormal tendency to bleed. In pediatrics, the examiner mainly wants you to recognize the bleeding pattern, because the pattern tells you where the defect is.
The key distinction:
Mucocutaneous bleeding
→ platelet number/function or von Willebrand disease
Deep bleeding into joints/muscles
→ coagulation factor deficiency, especially hemophilia
So your first clinical question is not “What is the platelet count?” but:
Is this platelet-type bleeding or coagulation-type bleeding?
Then confirm with basic hemostasis tests:
CBC + platelet count + smear
PT/INR
aPTT
fibrinogen
D-dimer if DIC suspected
Initial evaluation of bleeding disorders in children commonly begins with complete blood count, peripheral smear, prothrombin time, activated partial thromboplastin time, and fibrinogen. ([UpToDate][1])
Unlock the rest of this topic
Subscribe to Pediatrics for $10/month and unlock all 60 topics — full exam-structured notes, the State Exam questions integrated into every topic, and the downloadable Anki deck. Cancel anytime.
- ✓All 60 Pediatrics topics, exam-structured
- ✓State Exam questions in every topic
- ✓Downloadable Anki deck (.apkg)
- ✓Cancel anytime
Already subscribed? Sign in
